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Clinical Metagenomic Sequencing for Species Identification and Antimicrobial Resistance Prediction in Orthopaedic Device Infection

2021-08-17

Abstract excerpt

<h4>Background</h4> Diagnosis of orthopaedic device-related infection is challenging, and causative pathogens may be difficult to culture. Metagenomic sequencing can diagnose infections without culture, but attempts to detect antimicrobial resistance (AMR) determinants using metagenomic data have been less successful. Human DNA depletion may maximise the amount of microbial DNA sequence data available for analysis...

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Literature Corpus work
e0b29db7-04bc-5f6b-8c29-3ec0e3d79c04
DOI
10.1101/2021.08.13.21261967
Open publication

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Clinical Metagenomic Sequencing for Species Identification and Antimicrobial Resistance Prediction in Orthopaedic Device InfectionDOI 10.1101/2021.08.13.21261967
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