Article
Preliminary assessment of nanopore-based metagenomic sequencing for the diagnosis of prosthetic joint infection
18 May 2020
Abstract excerpt
OBJECTIVES: Pathogen identification is crucial for the diagnosis and management of periprosthetic joint infection (PJI). Although culturing methods are the foundation of pathogen detection in PJI, false-negative results often occur. Oxford nanopore sequencing (ONS) is a promising alternative for detecting pathogens and providing information on their antimicrobial resistance (AMR) profiles, without culturing....
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