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Application of rapid Nanopore metagenomic cell-free DNA sequencing to diagnose bloodstream infections: a prospective observational study

26 Mar 2025

Abstract excerpt

ABSTRACT Bloodstream infections are a major cause of mortality, often leading to sepsis or septic shock. Rapid initiation of effective antimicrobial therapy is essential for survival; however, the current gold standard for identifying pathogens in bloodstream infections, blood culturing, has limitations with long turnaround time and poor sensitivity. This delay in refining empirical broad-spectrum antimicrobial...

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Share to Bacterial Identification and Susceptibility Testing
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PMID: 40135889
DOI: 10.1128/spectrum.03295-24

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