Back to search

Article

An ultra-sensitive bacterial pathogen and antimicrobial resistance diagnosis workflow using Oxford Nanopore adaptive sampling sequencing method

2022-07-05

Abstract excerpt

Metagenomic sequencing analysis has been implemented as an alternative approach for pathogen diagnosis in recent years, which is independent on cultivation and able to identify all potential antibiotic resistant genes. However, current metagenomic sequencing analysis methods have to deal with low amounts of prokaryotic DNA and high amounts of host DNA in clinical samples, which significantly decrease the overall m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
77a9018b-e437-5e6f-bc79-28a13eb752a9
DOI
10.1101/2022.07.03.22277093
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An ultra-sensitive bacterial pathogen and antimicrobial resistance diagnosis workflow using Oxford Nanopore adaptive sampling sequencing methodDOI 10.1101/2022.07.03.22277093
Rapid Diagnosis of Lower Respiratory Infection using Nanopore-based Clinical MetagenomicsSemantic proximity
Molecular Rapid Diagnostic Testing for Bloodstream Infections: Nanopore Targeted Sequencing with Pathogen-Specific PrimersSemantic proximity
Optimizing and Evaluating Nanopore-Based Targeted and Metagenomic Sequencing Workflows for Rapid Diagnosis of Acute Invasive Infections from Normally Sterile Body FluidsSemantic proximity
Molecular rapid diagnostic testing for bloodstream infections: Nanopore targeted sequencing with pathogen-specific primersSemantic proximity
Metagenomic identification of pathogens and antimicrobial-resistant genes in bacterial positive blood cultures by nanopore sequencingSemantic proximity
Metagenomic Diagnosis for a Culture-Negative Sample From a Patient With Severe Pneumonia by Nanopore and Next-Generation SequencingSemantic proximity
Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencingSemantic proximity
Metagenomic identification of severe pneumonia pathogens with rapid Nanopore sequencing in mechanically-ventilated patientsSemantic proximity
The application of targeted nanopore sequencing for the identification of pathogens and resistance genes in lower respiratory tract infectionsSemantic proximity
Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity studySemantic proximity
Potential utility of targeted Nanopore sequencing for improving etiologic diagnosis of bacterial and fungal respiratory infectionSemantic proximity
Host DNA depletion assisted metagenomic sequencing of bronchoalveolar lavage fluids for diagnosis of pulmonary tuberculosisSemantic proximity
Select a neighboring publication to make it the new centre.