Article
[Kinase inhibitors].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 2010
Yamori Takao, Kong Dexin
Abstract excerpt
Various kinases phosphorylate their substrates and thereby switch on or off their functions. Dysregulation of kinases that regulate cell growth signals induces carcinogenesis or malignant phenotypes in cancer. Therefore, kinases are considered to be most promising therapeutic targets in cancer tr...
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