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Kinase Inhibitors and Kinase-Targeted Cancer Therapies: Recent Advances and Future Perspectives

17 May 2024

Abstract excerpt

Over 120 small-molecule kinase inhibitors (SMKIs) have been approved worldwide for treating various diseases, with nearly 70 FDA approvals specifically for cancer treatment, focusing on targets like the epidermal growth factor receptor (EGFR) family. Kinase-targeted strategies encompass monoclonal antibodies and their derivatives, such as nanobodies and peptides, along with innovative approaches like the use of...

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PMID: 38791529
DOI: 10.3390/ijms25105489

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