Article

Induction and long-term maintenance of hindbrain-like neural stem cells in xeno- and basic fibroblast growth factor-free conditions

2025-03-03

Abstract excerpt

<h4>SUMMARY</h4> Neurons exhibit region-specific identities corresponding to functional distinctions across different brain areas. Region-restricted neural stem cells (NSCs) have previously been generated from pluripotent stem cells; however, maintaining their regional identity over extended passages remains challenging. Here, we report the generation of hindbrain-like induced NSCs (Hb-LiNSCs) with upregulated hi...

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Literature Corpus work: e09290b7-b898-5f5c-af53-08e39a2ef813
DOI: 10.1101/2025.03.03.640169

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