Article
Preclinical Analysis of Fetal Human Mesencephalic Neural Progenitor Cell Lines: Characterization and Safety In Vitro and In Vivo.
Stem cells translational medicine - 1 Feb 2017
Moon Jisook, Schwarz Sigrid C, Lee Hyun-Seob, Kang Jun Mo, Lee Young-Eun, Kim Bona, Sung Mi-Young, Höglinger Günter, Wegner Florian, Kim Jin Su, Chung Hyung-Min, Chang Sung Woon, Cha Kwang Yul, Kim Kwang-Soo, Schwarz Johannes
Abstract excerpt
We have developed a good manufacturing practice for long-term cultivation of fetal human midbrain-derived neural progenitor cells. The generation of human dopaminergic neurons may serve as a tool of either restorative cell therapies or cellular models, particularly as a reference for phenotyping region-specific human neural stem cell lines such as human embryonic stem cells and human inducible pluripotent stem...
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