Article

Brainstem organoids from human pluripotent stem cells contain neural crest population

2019-11-04

Abstract excerpt

<h4>Summary</h4> The brainstem controls heartbeat, blood pressure and respiration, which are life-sustaining functions, therefore, disorders of the brainstem can be lethal. Brain organoids derived from human pluripotent stem cells recapitulate the course of human brain development and are expected to be useful for medical research on central nervous system disorders. However, existing organoid models have limitat...

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Literature Corpus work: fc58e111-caf6-5960-a5d9-01b9df4ba963
DOI: 10.1101/829275

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