Article

Electrochemical biosensors based on peptide-kinase interactions at the kinase docking site

2021-11-16

Abstract excerpt

Kinases are important cancer biomarkers and are conventionally detected based on their catalytic activity. Kinases regulate cellular activities by phosphorylation of motif-specific multiple substrate proteins, resulting in lack of selectivity of activity-based kinase biosensors. We present an alternative approach of sensing kinases based on the interactions of their allosteric docking sites with a specific partner...

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Literature Corpus work: e0916f84-0a24-5796-b401-4b1c545403db
DOI: 10.1101/2021.11.16.468793

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