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An electrochemical biosensor to identify the phenotype of aggressive breast cancer cells.

Chemical communications (Cambridge, England) - 28 Mar 2023

Wang Lin, Xie Haojie, Zhou Xinyi, Lin Yuxin, Qin Yujia, Yang Jie, Zhao Jing, Li Genxi

Abstract excerpt

Identifying the phenotype of aggressive breast cancer (BC) cells is vital for the effectiveness of surgical intervention and standard-of-care therapy. HER-2 is overexpressed in aggressive BC and MMP-2 is a crucial indicator of invasiveness and metastasis of BC, so we have proposed an electrochemical biosensor in this work to identify the phenotype of aggressive BC cells via detection of HER-2 together with MMP-2...

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PMID: 36916831
DOI: 10.1039/d3cc00611e

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