Article

Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1 mediated deacetylation of GLI1 and hepatic stellate cell activation

2020-12-02

Abstract excerpt

<h4>Background: </h4> and Purpose: Liver fibrosis is one of the leading causes of morbidity and mortality worldwide of which no acceptable therapy exists. Accumulating evidence supports that glioma-associated oncogene homologue 1(GLI1) is a potentially important therapeutic target for liver fibrosis. This study investigates the antifibrotic activities and potential mechanisms of Physalin B (PB), a natural Solanace...

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Literature Corpus work: e042e073-f52d-5673-af16-8b9b2bc4deaf
DOI: 10.22541/au.160688352.26104394/v1

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Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1 mediated deacetylation of GLI1 and hepatic stellate cell activationDOI 10.22541/au.160688352.26104394/v1Read

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