Article

Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages

2025-02-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The liver undergoes significant hemodynamic changes during surgery, transplantation, or cirrhosis with portal hypertension(PH). The hepatic artery buffer response(HABR), which compensates for reduced portal venous flow by increasing hepatic artery(HA) flow, is hypothesized to induce pathological portal tract remodeling. This study investigates the molecular mechanisms underl...

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Literature Corpus work: e03b54ab-5fcb-5d93-a4d4-4741a00fa21d
DOI: 10.1101/2025.01.31.634947

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