Article

The Liver is an Inflammatory Mediator of Pulmonary Arterial Hypertension

2025-10-06

Abstract excerpt

The liver’s contribution to pulmonary arterial hypertension (PAH) pathogenesis remains unclear. We hypothesized that the liver promotes inflammatory injury to the pulmonary endothelium. PAH patients without liver disease with pulmonary artery endothelial cell (PAEC) biopsies were included. Liver serologies and imaging were analyzed by unsupervised classification and regression tree (CART) to identify subclinical l...

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Literature Corpus work: c9f62dc7-c32b-5ed5-9132-ee0045cd89f9
DOI: 10.1101/2025.10.03.680270

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