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Comprehensive Mechanistic Investigation of Sanren Decoction in Ulcerative Colitis: Enhancement of the Intestinal Barrier, Modulation of Macrophage Polarization, and Regulation of Gut Microbiota

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>Sanren Decoction (SRD) has emerged as a promising therapeutic agent for ulcerative colitis (UC) due to its multifaceted mechanisms of action. This study employed an integrative methodology, including network pharmacology, molecular docking, and in vivo experimentation, to elucidate the underlying pharmacological mechanisms of SRD in UC management. The findings identified 87 genes target...

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Literature Corpus work
1903c024-2738-5ed0-b1da-8a8914b0e6b8
DOI
10.21203/rs.3.rs-6377473/v1
Open publication

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Comprehensive Mechanistic Investigation of Sanren Decoction in Ulcerative Colitis: Enhancement of the Intestinal Barrier, Modulation of Macrophage Polarization, and Regulation of Gut MicrobiotaDOI 10.21203/rs.3.rs-6377473/v1
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