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Deciphering the Nrf2/ARE Mechanism: GanCaoXieXin Decoction Combats Oxidative Stress in Ulcerative Colitis Pathogenesis

2025-07-08

Abstract excerpt

<h4>Background</h4> GanCaoXieXin (GCXX) decoction, a classic prescription, has shown clinical efficacy in treating ulcerative colitis (UC). However, its mechanism remains incompletely understood. <h4>Objective</h4> This study aims to explore how GCXX modulates the Nrf2/ARE signaling pathway to mitigate oxidative stress (OS)-induced damage and thereby ameliorate UC. <h4>Materials and methods</h4> Network pharmac...

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Literature Corpus work
4eed41d3-d56c-50ac-8c87-96d4a6d60487
DOI
10.1101/2025.07.02.662699
Open publication

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