Article

Regulation of cellular energy metabolism : implications for Parkinson's disease

2018-01-01

Abstract excerpt

Mutations in DJ-1 (PARK7) gene cause recessive, early-onset Parkinson‘s disease. DJ-1 is a neuroprotective oncogene that translocates from the cytoplasm to mitochondria under cellular stress conditions. The neuroprotective role of DJ-1 against reactive oxygen species has been extensively studied but its normal, physiological function is not fully understood. 14-3-3beta is a conserved protein of the 14-3-3 family o...

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Literature Corpus work: dfdb70f8-afda-54d5-a4cc-13ee33bbc316
DOI: 10.25560/62905

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