Article

Prediction of misfolded proteins spreading in Alzheimer’s disease using machine learning

2022-10-07

Abstract excerpt

The pervasive impact of Alzheimer’s disease on aging society represents one of the main challenges at this time. Current investigations highlight two specific misfolded proteins in its development: Amyloid- β and τ . Previous studies focused on spreading for misfolded proteins exploited simulations, which required several parameters to be empirically estimated. Here, we provide an alternative view based on a mac...

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Literature Corpus work: dfcb3365-51ee-5aa7-9763-ff947312d280
DOI: 10.1101/2022.10.04.510701

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