Article

Simulating the outcome of amyloid treatments in Alzheimer’s disease from imaging and clinical data

2020-09-03

Abstract excerpt

In this study we investigate a novel quantitative instrument for the development of intervention strategies for disease modifying drugs in Alzheimer’s disease. Our framework is based on the modeling of the spatio-temporal dynamics governing the joint evolution of imaging and clinical biomarkers along the history of the disease, and allows the simulation of the effect of intervention time and drug dosage on the bio...

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Identifiers and source

Literature Corpus work: 2a68dcaf-e53e-54ef-9c76-fac2e4647dec
DOI: 10.1101/2020.09.02.279521

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