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Detection of ctDNA from dried blood spots after DNA size selection

2019-09-05

Abstract excerpt

Recent advances in the research and clinical applications of circulating tumour DNA (ctDNA) is limited by practical considerations of sample collection. Whole genome sequencing (WGS) is increasingly used for analysis of ctDNA, identifying copy-number alterations, fragment size patterns, and other genomic features. We hypothesised that low-depth WGS data may be generated from minute amounts of cell-free DNA, and th...

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Literature Corpus work
dfb8b336-13c3-5c3e-98d3-b5887f109010
DOI
10.1101/759365
Open publication

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Detection of ctDNA from dried blood spots after DNA size selectionDOI 10.1101/759365
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