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Article

Detection of BRAF-V600E and V600K in melanoma circulating tumour cells by droplet digital PCR.

Clinical biochemistry - 1 Oct 2015

Reid Anna L, Freeman James B, Millward Michael, Ziman Melanie, Gray Elin S

Abstract excerpt

OBJECTIVES: Defining the BRAF mutation status in metastatic melanoma patients is critical to selecting patients for therapeutic treatment with targeted therapies. Circulating tumour cells (CTCs) can provide an alternative source of contemporaneous tumour genetic material. However methodologies to analyse the presence of rare mutations in a background of wild-type DNA requires a detailed assessment. Here we...

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Source

Identifiers

PMID: 25523300
DOI: 10.1016/j.clinbiochem.2014.12.007

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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