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Article

Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy.

Molecular diagnosis & therapy - 1 Jul 2023

Fitzgerald Sandra, Blenkiron Cherie, Stephens Rosalie, Mathy Jon A, Somers-Edgar Tiffany, Rolfe Gill, Martin Richard, Jackson Christopher, Eccles Michael, Robb Tamsin, Rodger Euan, Lawrence Ben, Guilford Parry, Lasham Annette, Print Cristin G

Abstract excerpt

BACKGROUND: Circulating tumour DNA (ctDNA) analysis promises to improve the clinical care of people with cancer, address health inequities and guide translational research. This observational cohort study used ctDNA to follow 29 patients with advanced-stage cutaneous melanoma through multiple cycles of immunotherapy. METHOD: A melanoma-specific ctDNA next-generation sequencing (NGS) panel, droplet digital...

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Share to Circulating Tumor DNA
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunotherapy

Share to Melanoma

Share to Melanoma, Cutaneous Malignant

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 37099071
DOI: 10.1007/s40291-023-00651-4
PMCID: PMC10131510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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