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Article

Lambda Interferon Inhibits Hepatitis B and C Virus Replication

24 Feb 2005

Abstract excerpt

Lambda interferon (IFN-lambda) induces an intracellular IFN-alpha/beta-like antiviral response through a receptor complex distinct from the IFN-alpha/beta receptor. We therefore determined the ability of IFN-lambda to inhibit hepatitis B virus (HBV) and hepatitis C virus (HCV) replication. IFN-lambda inhibits HBV replication in a differentiated murine hepatocyte cell line with kinetics and efficiency similar to...

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Identifiers

PMID: 15731279
DOI: 10.1128/jvi.79.6.3851-3854.2005

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