Article

Lineage tracing and live-cell imaging reveal that NeuroD1 does not reprogram microglia into neurons

2026-06-09

Abstract excerpt

Induction of glia-to-neuron conversion is a promising regenerative strategy for treating brain injuries and neurodegenerative diseases. Previous studies have suggested that NeuroD1 can induce microglia-to-neuron cross-lineage conversion. However, it remains highly controversial. To conclusively determine whether NeuroD1 can convert microglia into neurons, we used genetic fate mapping to track the cell fate of micr...

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Literature Corpus work: df9c4a8f-9efd-59c9-992a-6aef98f25cbb
DOI: 10.64898/2026.06.08.730780

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