Article

Dynamic regulation of NeuroD1 expression level by a novel viral construct during astrocyte-to-neuron reprogramming

2025-02-20

Abstract excerpt

Astrocyte-to-neuron reprogramming presents a viable approach for regenerative medicine. The reprogramming factor NeuroD1 has demonstrated capability of neuronal reprogramming with high efficiency both in culture and in the injured central nervous system. High level of NeuroD1 expression is required to break down the cellular identity barrier for a successful reprogramming, and yet persistence of this high level dr...

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Literature Corpus work: a72af72d-f988-58c5-8fd7-0ff4eb807ddb
DOI: 10.1101/2025.02.17.638625

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