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Article

Tensor decomposition reveals coordinated multicellular patterns of transcriptional variation that distinguish and stratify disease individuals

2022-02-18

Abstract excerpt

<h4>Summary</h4> Tissue- and organism-level biological processes often involve coordinated action of multiple distinct cell types. Current computational methods for the analysis of single-cell RNA-sequencing (scRNA-seq) data, however, are not designed to capture co-variation of cell states across samples, in part due to the low number of biological samples in most scRNA-seq datasets. Recent advances in sample mul...

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Literature Corpus work
df968ca6-7cde-5a84-82c3-73c55a627feb
DOI
10.1101/2022.02.16.480703
Open publication

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Tensor decomposition reveals coordinated multicellular patterns of transcriptional variation that distinguish and stratify disease individualsDOI 10.1101/2022.02.16.480703
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