Article

Single-cell transcriptome landscape of circulating CD4 <sup>+</sup> T cell populations in human autoimmune diseases

2023-05-10

Abstract excerpt

CD4 + T cells are a key mediator of various autoimmune diseases; however, how they contribute to disease development remains obscure primarily because of their cellular heterogeneity. Here, we evaluated CD4 + T cell subpopulations by decomposition-based transcriptome characterization together with canonical clustering strategies. This approach identified 12 independent transcriptional gene programs governing who...

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Literature Corpus work: fc79e971-0bd6-5ee2-a81e-64de39d038e3
DOI: 10.1101/2023.05.09.540089

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