Article

Post transcriptional regulation of microRNAs in embryonic stem cells

2018-01-01

Abstract excerpt

In this project a block in processing of primary miRNA transcripts (pri-miRNAs) in human embryonic stem cells was demonstrated. Pri-miRNAs for 15 out of 24 tested intergenic miRNAs were detected by RT-PCR in the H1 cell line despite a lack of detection of their mature form in deep sequencing data. By contrast, only 2 out of 16 pri-miRNAs for which expression of the mature form was not reported were successfully am...

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Literature Corpus work: df6cf4b1-4240-5916-8376-54830212a2ec
DOI: 10.25560/59074

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