Article

Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing

2020-05-02

Abstract excerpt

MicroRNA expression is important for gene regulation and deregulated microRNA expression is often observed in disease such as cancer. The processing of primary microRNA transcripts is an important regulatory step in microRNA biogenesis. Due to low expression level and association with chromatin primary microRNAs are challenging to study in clinical samples where input material is limited. Here, we present a high-s...

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Literature Corpus work: e10bb145-5672-5b67-a056-c2434522fe74
DOI: 10.1101/2020.04.30.070912

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