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Article

MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells

23 Mar 2009

Abstract excerpt

BACKGROUND: The unique features of human embryonic stem (hES) cells make them the best candidate resource for both cell replacement therapy and development research. However, the molecular mechanisms responsible for the simultaneous maintenance of their self-renewal properties and undifferentiated state remain unclear. Non-coding microRNAs (miRNA) which regulate mRNA cleavage and inhibit encoded protein...

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PMID: 19309508
DOI: 10.1186/1479-5876-7-20

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