Article

Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans

2018-01-05

Abstract excerpt

The CRISPR-Cas9 system has proven to be a powerful tool for genome editing, allowing for the precise modification of specific DNA sequences within a cell. Many efforts are currently underway to use the CRISPR-Cas9 system for the therapeutic correction of human genetic diseases. The most widely used homologs of the Cas9 protein are derived from the bacteria Staphylococcus aureus ( S. aureus ) and Streptococcus p...

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Literature Corpus work: df67f99a-5e11-5c2f-8b65-b71e1606d1cf
DOI: 10.1101/243345

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