Article

Blood and Brain Gene Expression Trajectories Underlying Neuropathology and Cognitive Impairment in Neurodegeneration

2019-02-13

Abstract excerpt

<h4>SUMMARY</h4> Neurodegenerative disorders take decades to develop and their early detection is challenged by confounding non-pathological aging processes. For all neurodegenerative conditions, we lack longitudinal gene expression (GE) data covering their large temporal evolution, which hinders the fully understanding of the underlying dynamic molecular mechanisms. Here, we aimed to overcome this limitation by...

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Literature Corpus work: df520d88-66ee-5737-b2b8-1a65830f2863
DOI: 10.1101/548974

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