Article

Modeling Temporal Dependencies and Feature Interactions Reveal Novel Clinical and Molecular Insights into Alzheimer’s Disease Progression

2025-12-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Alzheimer’s Disease remains a major public health challenge, requiring insights into feature interactions and temporal trends of feature importance. Community-wide data science competitions such as the TADPOLE Challenge provide platforms to benchmark predictive models using ADNI datasets. While top-performing models achieve accurate predictions, they often leave mechanistic q...

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Literature Corpus work: b4595b7b-246f-58f7-a432-5af96848e388
DOI: 10.1101/2025.11.27.690894

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