Article

Sequence-to-function deep learning frameworks for synthetic biology

2019-12-10

Abstract excerpt

While synthetic biology has revolutionized our approaches to medicine, agriculture, and energy, the design of novel circuit components beyond nature-inspired templates can prove itself challenging without well-established design rules. Toehold switches — programmable nucleic acid sensors — face an analogous prediction and design bottleneck: our limited understanding of how sequence impacts functionality can requir...

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Literature Corpus work: df4097ff-e434-588d-a191-8860d26f5dfb
DOI: 10.1101/870055

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