Article

The Use of Molecular Markers to Investigate Possible Resistance to Heartworm Preventives in Dirofilaria Immitis Samples from Heartworm Positive Dogs in Europe

2021-09-14

Abstract excerpt

<h4>Background: </h4> Dirofilaria immitis is a parasitic filarial nematode. It is the causative agent of dirofilariosis, a potentially fatal pulmonary infection which primarily infects canids and felines. dirofilariosis infections are primarily controlled with a prophylactic macrocyclic lactone (ML) regimen. Recent evidence has confirmed the development of ML-resistant isolates in the US which are genetically dist...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dec4781f-45d3-5ab8-a443-4ad70bdf0a61
DOI: 10.21203/rs.3.rs-864621/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Use of Molecular Markers to Investigate Possible Resistance to Heartworm Preventives in Dirofilaria Immitis Samples from Heartworm Positive Dogs in EuropeDOI 10.21203/rs.3.rs-864621/v1Read

Dirofilaria Immitis: Genotyping European Clinical Samples and US Laboratory Isolates at Single Nucleotide Polymorphic (SNP) Sites Associated With Macrocyclic Lactone Susceptibility and ResistanceSemantic proximity Read

Dirofilaria immitis: Genotyping Randomly Selected European Clinical Samples and USA Laboratory Isolates with Molecular Markers Associated with Macrocyclic Lactone Susceptibility and ResistanceSemantic proximity Read

Clinical validation of molecular markers of macrocyclic lactone resistance in Dirofilaria immitis.Semantic proximity Read

Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives.Semantic proximity Read

Genotyping USA laboratory-maintained isolates and European clinical isolates of Dirofilaria immitis to assess macrocyclic lactone susceptibility or resistance at predictive SNP sites using droplet digital PCR.Semantic proximity Read

Surveillance of single nucleotide polymorphisms correlated to macrocyclic lactone resistance in Dirofilaria immitis from client-owned dogs across the United States.Semantic proximity Read

Macrocyclic lactone resistance in Dirofilaria immitis: Failure of heartworm preventives and investigation of genetic markers for resistance.Semantic proximity Read

First case of macrocyclic lactone-resistant Dirofilaria immitis in Europe - Cause for concern.Semantic proximity Read

Droplet digital PCR as a tool to detect resistant isolates of Dirofilaria immitisSemantic proximity Read

Concern for <em>Dirofilaria immitis</em> and Macrocyclic Lactone Loss of Efficacy: Current Situation in the USA and Europe, and Future ScenariosSemantic proximity Read

Dirofilaria immitis JYD-34 isolate: whole genome analysis.Semantic proximity Read

Can P-glycoprotein and β-tubulin polymorphisms be used as genetic markers of resistance in Dirofilaria immitis from Rio de Janeiro, Brazil?Semantic proximity Read