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Article

First case of macrocyclic lactone-resistant Dirofilaria immitis in Europe - Cause for concern.

International journal for parasitology. Drugs and drug resistance - 1 Aug 2024

Traversa Donato, Diakou Anastasia, Colombo Mariasole, Kumar Sohini, Long Thavy, Chaintoutis Serafeim C, Venco Luigi, Betti Miller Gianluca, Prichard Roger

Abstract excerpt

Heartworm disease caused by the nematode Dirofilaria immitis is one of the most important parasitoses of dogs. The treatment of the infection is long, complicated, risky and expensive. Conversely, prevention is easy, safe, and effective and it is achieved by the administration of macrocyclic lactones (MLs). In recent years, D. immitis strains resistant to MLs have been described in Southern USA, raising concerns...

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Identifiers

PMID: 38795510
DOI: 10.1016/j.ijpddr.2024.100549
PMCID: PMC11153229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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