Article
Genotyping USA laboratory-maintained isolates and European clinical isolates of Dirofilaria immitis to assess macrocyclic lactone susceptibility or resistance at predictive SNP sites using droplet digital PCR.
Veterinary parasitology - 1 Jun 2024
Kumar Sohini, Che Hua, Chiummo Rafael, Heuer Lea, Schneider Carolin, Werr Margaret, Guerino Frank, Papadopolous Elias, Diakou Anastasia, Mihalca Andrei Daniel, Traversa Donato, Di Cesare Angela, Long Thavy, Prichard Roger K
Abstract excerpt
Dirofilaria immitis is a parasitic nematode that causes cardiovascular dirofilariosis ("heartworm disease") primarily in canids. The principal approach for mitigating heartworm infection involves the use of macrocyclic lactone (ML) for prophylaxis. Recent research has substantiated the emergence of D. immitis displaying resistance to MLs in the USA. Numerous factors, such as the mobility of companion animals and...
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