Article
Droplet digital PCR as a tool to detect resistant isolates of Dirofilaria immitis
23 Jul 2023
Abstract excerpt
Prevention of canine heartworm disease, caused by Dirofilaria immitis, relies on macrocyclic lactones for which drug resistance is now a concern. Although genetic polymorphisms have been associated with resistance in D. immitis populations, the mechanism is still not well understood. The lack of reliable in vitro assays to detect resistance is a limitation for confirming resistance. Ten single nucleotide...
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