Article
From transcriptional complexity to cellular phenotypes: Lessons from yeast.
Yeast (Chichester, England) - 1 Dec 2017
Pelechano Vicent
Abstract excerpt
Pervasive transcription has been reported in many eukaryotic organisms, revealing a highly interleaved transcriptome organization that involves thousands of coding and non-coding RNAs. However, to date, the biological impact of transcriptome complexity is still poorly understood. Here I will review how subtle variations of the transcriptome can lead to divergent cellular phenotypes by fine-tuning both its coding...
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