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Article

Apolipoprotein E ϵ4 and Incidence of Alzheimer Disease in a Community Population of Older Persons

1997-03-12

Abstract excerpt

Objective. —To examine the relation between apolipoprotein E status and risk of Alzheimer disease (AD) in a defined population and estimate the fraction of incident AD attributable to the ϵ4 allele. Design. —Community-based cohort study. Setting. —East Boston, Mass. Participants. —A random sample of 578 community residents aged 65 years and older free of AD. Main Outcome Measure. —Clinical diagnosis of AD by unifo...

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Literature Corpus work
deaef3ec-8629-5d7a-8041-c029de523932
DOI
10.1001/jama.1997.03540340056033
Open publication

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Apolipoprotein E ϵ4 and Incidence of Alzheimer Disease in a Community Population of Older PersonsDOI 10.1001/jama.1997.03540340056033
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