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Article

Apolipoprotein E genotype, dementia, and mortality in the oldest old: the 90+ Study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2013

Corrada María M, Paganini-Hill Annlia, Berlau Daniel J, Kawas Claudia H

Abstract excerpt

BACKGROUND: Although the apolipoprotein E (APOE) ε4 allele is a major genetic risk factor for Alzheimer's disease (AD), it is not clear whether this relationship persists among the oldest old. Several European studies suggest that the effect of the APOE ε4 allele on dementia and mortality disappears in very old age. We describe the APOE allele and genotype frequencies and examine whether the presence of the APOE...

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Source

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Identifiers

PMID: 23123227
DOI: 10.1016/j.jalz.2011.12.004
PMCID: PMC3543489

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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