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Treatment with carnosic acid attenuates the secretion of pro-inflammatory mast cell mediators following IL-33 activation

2024-10-01

Abstract excerpt

IL-33 is an alarmin cytokine, released upon cellular damage, that has gained significant attention as a regulator of inflammation in several pathologies, including allergy. Once released, IL-33 binds to and activates its cognate receptor ST2, leading to the activation of the classical inflammatory Myddosome signalosome in an array of cells, including mast cells. Our group has recently identified the polyphenol car...

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Literature Corpus work
dea16d0e-0b36-582a-b289-bb3223a2fbd0
DOI
10.1101/2024.09.29.615684
Open publication

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Treatment with carnosic acid attenuates the secretion of pro-inflammatory mast cell mediators following IL-33 activationDOI 10.1101/2024.09.29.615684
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