Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epithelial cells expressed IL-33 to promote degranulation of mast cells through inhibition on ST2/PI3K/mTOR-mediated autophagy in allergic rhinitis

16 Apr 2020

Abstract excerpt

Nasal epithelial cells are the first barrier against allergen infiltration in allergic rhinitis (AR), and the relationship between nasal epithelial cells and mast cell-mediated hypersensitivity remains unclear. This study aimed to investigate the possible association between allergen-challenged nasal epithelial cells (AR-HNEpC) and mast cell degranulation in AR. Our data revealed that calcium influx and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways
Share to Mast cells and histamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32298206
DOI: 10.1080/15384101.2020.1749402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epithelial cells expressed IL-33 to promote degranulation of mast cells through inhibition on ST2/PI3K/mTOR-mediated autophagy in allergic rhinitisPMID 32298206Read ↗

IL-21 induces pyroptosis of Treg cells via Akt–mTOR–NLRP3–caspase 1 axis in eosinophilic chronic rhinosinusitisSemantic proximity Read ↗

Treatment with carnosic acid attenuates the secretion of pro-inflammatory mast cell mediators following IL-33 activationSemantic proximity Read ↗

The Roles of Autophagy, Mitophagy, and the Akt/mTOR Pathway in the Pathogenesis of Chronic Rhinosinusitis with Nasal PolypsSemantic proximity Read ↗

The role of autophagy regulated by the PI3K/AKT/mTOR pathway and innate lymphoid cells in eosinophilic chronic sinusitis with nasal polypsSemantic proximity Read ↗

Mast cells in allergic airway disease and chronic rhinosinusitis.Semantic proximity Read ↗

Autophagy-Related Genes Are Involved in the Progression and Prognosis of Asthma and Regulate the Immune MicroenvironmentSemantic proximity Read ↗

Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitisSemantic proximity Read ↗

Oxidative Stress and PRKN-Mediated Senescence Link RhoA/ROCK Signaling to Epithelial Remodeling in Allergic RhinitisSemantic proximity Read ↗

Regulation of Osteoclastogenesis by Mast Cell in Rheumatoid ArthritisSemantic proximity Read ↗

Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammationSemantic proximity Read ↗

Interleukin‐33 in allergySemantic proximity Read ↗

Asthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.