Article

Physical basis for the interaction between <i>Drosophila</i> ROS1 and the GPCR BOSS

2024-03-14

Abstract excerpt

<h4>Abstract/Summary</h4> Drosophila ROS1 (dROS1, Sevenless) is a receptor tyrosine kinase (RTK) essential for the differentiation of Drosophila R7 photoreceptor cells 1, 2 . Activation of dROS1 is mediated by binding to the extracellular region (ECR) of the GPCR (G protein coupled receptor) BOSS (Bride Of Sevenless) on adjacent cells 1, 3, 4 . Genetic evidence together with in vitro activity assays confirmed...

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Literature Corpus work: de6f5668-ae96-50fd-a655-6b09e6c66a2a
DOI: 10.1101/2024.03.13.584817

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