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Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and Reactivation

20 Aug 2018

Abstract excerpt

Human cytomegalovirus (HCMV) is a beta herpesvirus that establishes a life-long persistence in the host, like all herpesviruses, by way of a latent infection. During latency, viral genomes are maintained in a quieted state. Virus replication can be reactivated from latency in response to changes in cellular signaling caused by stress or differentiation. The past decade has brought great insights into the...

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PMID: 30127257
DOI: 10.3390/v10080444

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