Article

Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency

2020-02-06

Abstract excerpt

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that latently infects hematopoietic cells and has the ability to reactivate when triggered by immunological stress. This reactivation causes significant morbidity and mortality in immune-deficient patients, who are unable to control viral dissemination. While a competent immune system helps prevent clinically detectable viremia, a portrait of the factors that i...

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Literature Corpus work: 7c7814a5-2f24-52cf-9e2c-40b4070b9718
DOI: 10.1101/2020.02.06.929281

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