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A novel quinazoline derivative induces apoptosis and modulates EGFR/PI3K/AKT/mTOR-related gene expression in glioblastoma cells

2026-07-08

Abstract excerpt

<title>Abstract</title> <p> Glioblastoma multiforme (GBM) remains one of the most aggressive and treatment-resistant brain tumors, highlighting the urgent need for novel therapeutic approaches. In this study, we synthesized and characterized a series of quinazoline derivatives and evaluated their antitumor potential in human glioblastoma cells. Among the synthesized compounds, N²-(4-(benzyloxy)phenyl)-6,7-dimeth...

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Literature Corpus work
ddfee31e-4b49-5fba-97ce-94197fc69b5d
DOI
10.21203/rs.3.rs-10241279/v1
Open publication

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A novel quinazoline derivative induces apoptosis and modulates EGFR/PI3K/AKT/mTOR-related gene expression in glioblastoma cellsDOI 10.21203/rs.3.rs-10241279/v1
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