Article

Cytotoxic activity, apoptosis induction and cell cycle arrest in human breast cancer (MCF7) cells by a novel fluorinated tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin chalcones

2021-05-18

Abstract excerpt

<title>Abstract</title> <p>A series of halogenated chalcones (<bold>3–8</bold>) was synthesized and confirmed by several spectral tools. The cytotoxic effect of this series was tested against a panel of different cancer cell lines (MCF7, A549, HCT116, and PC3). Our MTT assay results revealed that chalcone <bold>8</bold> had the potent cytotoxic activity against all tested cancer cell lines except A549 cells, whic...

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Literature Corpus work: eb0b5ba5-e314-5c76-b1d9-3cb91218308e
DOI: 10.21203/rs.3.rs-496965/v1

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