Article

Activated NK cells with a predominance of inhibitory receptors and a decidual-like phenotype expand after autologous HSCT in children with tumors

2024-07-03

Abstract excerpt

<h4>SUMMARY</h4> Early immune reconstitution after autologous hematopoietic stem cell transplantation (autoHSCT) is associated with a better outcome in a variety of cancers. NK cells constitute the first lymphocyte subset to recover in the blood after autoHSCT. We have in-depth characterized them in pediatric patients with different tumors and found that, immediately after autoHSCT, NK cells transiently acquired...

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Literature Corpus work: b0c36ecf-00d0-5314-b504-9328df0b7aa2
DOI: 10.1101/2024.07.01.601507

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