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Article

Three differentiation states risk-stratify bladder cancer into distinct subtypes

19 Jan 2012

Abstract excerpt

Current clinical judgment in bladder cancer (BC) relies primarily on pathological stage and grade. We investigated whether a molecular classification of tumor cell differentiation, based on a developmental biology approach, can provide additional prognostic information. Exploiting large preexisting gene-expression databases, we developed a biologically supervised computational model to predict markers that...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 22308455
DOI: 10.1073/pnas.1120605109

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